These parameters include age, preoperative serum prostate-specific antigen (PSA) concentration, body mass index (BMI), tumor diameter, Grade group (GG) and Gleason score (GS), lymphatic, venous, perineural, and seminal vesicle invasion, extraprostatic extension (EPE) of the tumor, positive surgical margins, and lymph node metastasis (10). This evidence concerns the gene KLK3 and metastatic malignant neoplasm in the lymph nodes.