SELE and neoplasm: Consistent with our previous findings showing that asTF promotes neovascularization and macrophage infiltration by binding α6β1 and αvβ3 integrins expressed on endothelial cells, which triggers new vessel formation and, concomitantly, the expression of such cell adhesion molecules as E-selectin, VCAM1, and ICAM1 (3, 6, 22), we found that hRabMab1 suppresses neovascularization as well as macrophage infiltration in the tumor tissue.