Four factors including bone metastasis (HR = 1.781, P = 0.026), PVTT (HR = 2.078, P = 0.015), AFP (HR = 2.098, P = 0.007) and radiation dose (HR = 0.535, P = 0.023) have significant potential to predict survival (Table 2). The gene discussed is AFP; the disease is bone metastasis.