The results showed that the high Gankyrin expression was positively related to CEA level (p < 0.001), advanced TNM stage (p < 0.001), liver metastasis (p < 0.001) and lymph node metastasis (p < 0.001) in CRC patients (Table 1). This evidence concerns the gene PSMD10 and metastatic malignant neoplasm in the lymph nodes.