PTK2 and Miyoshi myopathy: So as to determine whether circ-PTK2 was dysregulated in MM cell lines, RT-qPCR was performed, which observed that expression of Circ-PTK2 was upregulated in NCI-H929 (P<0.01), LP-1 (P<0.001) and RPM1-8226 cells (P<0.05) but similar in U266 cells (P>0.05) compared with control (Figure 1).