KLK8 and familial pancreatic carcinoma: Based on the indicated role of KLK8 in malignant disease found in GEPIA (http://gepia.cancer-pku.cn/detail.php?gene=KLK8) (Figure 1A), we analyzed the expression of KLK8 in the independent public dataset from Oncomine (https://www.oncomine.org/resource/main.html) and found that KLK8 expression was elevated in the pancreatic cancer tissue samples in comparison to the normal pancreas (Figure 1B, P<0.0001).