Results demonstrated a lower level of ST5 expression in multiple molecular subtypes of breast cancer tissue, including Luminal B subtype (n=667), Luminal A subtype (n=1,595), HER2-E subtype (n=641) and Basal-like subtype (n=625), than in normal breast tissue (n=839) (P < 0.01) (Figure 1A). This evidence concerns the gene ERBB2 and breast cancer.