Guo et al. (2020) reported that m6A and its regulator, HNRNPA2B1, were significantly elevated in esophageal cancer. They also reported that HNRNPA2B1 played a carcinogenic role in esophageal cancer cell progression. Xu, Pan & Pan (2020) constructed and validated an m6A RNA methylation regulators-based signature as an independent prognostic predictor for esophageal cancer patients. The gene discussed is HNRNPA2B1; the disease is esophageal cancer.