The Venn analysis (Supplement S7) showed that PTGS2, PGR, BAX, CASP8, TGFB1, CASP3, BCL2, GSTP1, GSTM1, IL1B, MMP2, CDKN1A, POLD1, TP53, IL6, TNF, and ESR1, existed for all three core prescriptions and CRC. Here, MMP2 is linked to colorectal carcinoma.