INS and Hypoglycemia: 3–6 Hypoglycemia in non-diabetic patients is considered a rare event, occurring in less than 1% of all hospitalizations.7 Reported causes of hypoglycemia in non-diabetic patients include reactive hypoglycemia, insulin-secreting tumours and other malignancies, hypopituitarism, hypocortisolism, alcohol abuse, inappropriate insulin self-administration, malnutrition, renal failure and sepsis.8 – 11