Cuiling Zhou et al. collected 128 samples of primary NSCLC after surgical resection and tested the expression of PD-L1 by immunohistochemistry, revealing that the overall survival (OS) of the PD-L1 negative expression group was remarkably longer than that of the PD-L1 positive expression group (Zhou et al., 2019). The gene discussed is CD274; the disease is non-small cell lung carcinoma.