LAMA2 and congenital muscular dystrophy: Likewise, muscles or muscle-derived cells from LAMA2-CMD patients were described as having an abnormal membrane potential (Fontes-Oliveira et al., 2017), impaired mitochondrial function and bioenergetic status and downregulation of a variety of mitochondrial related genes (Fontes-Oliveira et al., 2017; Kölbel et al., 2019).