To determine whether ZIKV infection affected immune function, we assessed the expression of HLA-DR (activation), CXCR3 (activation and trafficking), Ki67 (activation and proliferation), and granzyme B (cytotoxicity) on decidual T lymphocytes in ZIKV-infected dams and compared with decidua of normal pregnancies. This evidence concerns the gene MKI67 and Zika virus infectious disease.