CXCR3 and Autoimmunity: It is possible that ZIKV induces autoimmunity of the circulating leukocytes while at the tissue-level of the already tolerant maternal-fetal interface, the immune cell environment is silenced by loss of T cell activation and reduced infiltration of CXCR3-expressing CD4+ and CD8+ T lymphocytes which are inflammation-homing T cells.