The TLR Signaling Pathway, Regulation of toll-like receptor signaling pathway, Spinal Cord Injury, AGE/RAGE pathway, Oncostatin M Signaling Pathway, PI3K-Akt Signaling Pathway, and Photodynamic therapy-induced NF-kB survival signaling in WIKI were important biological function pathways in the host factor interaction networks, as shown in Table 1. This evidence concerns the gene NFKB1 and spinal cord injury.