After collating COVID-19- and dengue-associated targets, these two target categories were compared and filtered to identify common elements using the web tools provided by the Van de Peer Lab. Ultimately, 460 common host factors were obtained, including MMP2, PDF, PFKP, SLC25A3, IGF1, CCL4, TLR4, and AhR. The gene discussed is TLR4; the disease is dengue disease.