Univariate Cox regression analysis to screen 18 prognostic-related factors, it was found that LOXL2, PTX3, SLC2A1, RTKN2, ANLN, NFIX, CALU, ERO1A, BMP2, FSCN1, COL1A2, SLC16A1, COL3A1, MME, SNX30, COL1A1, and MSI2 might be prognostic risk factors of NSCLC patients (Table 3). The gene discussed is CALU; the disease is non-small cell lung carcinoma.