In patients with MS, the level of 1,25(OH)2D3-induced CYP24A1 mRNA expression in PBMCs was significantly and negatively correlated with serum 25(OH)D3 (for ΔCT, r=0.744, p=0.014); however, no significant association was found for VDR, CYP27B1, and IL-10 mRNA expression (Figure 5). The gene discussed is IL10; the disease is myeloid sarcoma.