The 26 proteins were then assessed for allergenicity using AllergGAtlas database (http://biokb.ncpsb.org/AlleRGatlas/) (48) and 4 allergy related proteins, including beta-actin (ACTB), fatty acid-binding protein 5 (FABP5), protocadherin 11 (PCDH11X), and myomegalin (PDE4DIP) were identified. The gene discussed is PDE4DIP; the disease is allergic disease.