NFE2L2 and metabolic dysfunction-associated steatotic liver disease: Apigenin (API), a peroxisomal proliferator-activated receptor γ modulator (PPARM), improves the lipid accumulation and oxidative stress of NAFLD by regulating Nrf2 and PPARγ in mice (Panda and Kar, 2007; Tong and Pelling, 2013; Feng et al., 2017).