GFAP and glaucoma: Indeed, oxidative stress has been recognized as playing a pivotal role in the development of inflammation (Gill et al., 2010; Reuter et al., 2010), which, in glaucoma, would induce macroglial cell activation, characterized by increased glial fibrillary acidic protein (GFAP) expression in Müller cells (Mélik Parsadaniantz et al., 2020), and a marked release of cytokines/chemokines that would damage retinal neurons (Chen et al., 2010).