Given that TMP reduces the infarct volume (Xiao et al., 2010; Kao et al., 2013) and upregulates MCPIP1 in the context of stroke in mice, it is reasonable to postulate that the neuroprotective effects of TMP may, at least in part, be related to the induction of MCPIP1. This evidence concerns the gene ZC3H12A and stroke disorder.