The expressions of Acat2 (ENSMUST00000159697), Pgrmc2 (ENSMUST00000058578), Acox1 (ENSMUST000000666587), Acox1 (ENSMUST00000072948), Mup3 (ENSMUST0000007488), Mup3 (ENSMUST 0000007472), Mup20 (ENSMUST00000074018), Slc22a28 (ENSMUST00000065651) and Slco1a1 (ENSMUST00000042119) were down-regulated in the AF group, which was consistent with the sequencing results (Supplementary Table S4). The gene discussed is PGRMC2; the disease is atrial fibrillation.