According to some literature, the herbs of PL, LS, AS, AP, SG, AB, TC, the major constitutes of Duhuo-Jisheng decoction, were commonly used for RA treatment in the clinic (Zhang et al., 2020), and tetrandrine, one of the main ingredients of ST, was reported to alleviate symptoms of RA through regulating NF-κB and MAPK signaling pathways (Wu et al., 2020). This evidence concerns the gene NFKB1 and rheumatoid arthritis.