Among them, target genes with degrees higher than average were TNF, JUN, IL-6, IL-1B, NFKBIA, TP53, CASP3, IFNG, BCL2, CASP8 and BAX (Table 5), which may be important targets for Shenfu injection in the treatment of IPF. The gene discussed is TP53; the disease is idiopathic pulmonary fibrosis.