Multiple ECM proteins such as fibronectin and periostin are known to be more abundant in lung tissue of patients with IPF (Naik et al., 2012; Lehtonen et al., 2016; Tomos et al., 2017; Kudo and Kii, 2018), but collagens are the most abundant. This evidence concerns the gene POSTN and idiopathic pulmonary fibrosis.