IL1B and post-traumatic stress disorder: In addition to IL1B and ILK, pathway analysis of all gene expression probes nominally associated with PTSD revealed an enrichment of toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) genes that share the conserved toll/IL-1R homologous region (TIR) and are involved in innate antibacterial and antifungal immunity, consistent with previous reports from gene expression (Breen et al., 2015) and methylation studies (Uddin et al., 2010; Smith et al., 2011) in PTSD.