For GSE66890 dataset, there were 370 significantly enriched BP terms including neutrophil degranulation/activation, neutrophil mediated immunity and DNA packaging (p < 0.05), 62 significantly enriched CC terms including secretory granule lumen and cytoplasmic vesicle lumen (p < 0.05), 22 significantly enriched MF terms including protein heterodimerization activity, cadherin binding and actin filament binding (p < 0.05), and seven significantly enriched KEGG pathways including systemic lupus erythematosus, phagosome and hematopoietic cell lineage (p < 0.05). The gene discussed is CDH17; the disease is systemic lupus erythematosus.