Remarkably, we found higher TNF, IL-1β, IL-6, and IL-10 in lung homogenates of LysM-cre × Hif1αfl/fl mice when compared with Hif1αfl/fl control mice at 12 hours after inoculation, but these differences in pulmonary cytokine levels were not present after 40 hours of infection. This evidence concerns the gene IL10 and infection.