It is known that E3 ubiquitin-protein ligase WWP1 is linked to oral cancer [6-12].Therefore, it is of interest to document molecular docking data of E3 ubiquitin-protein ligase WWP1 with compounds ((Stigmasterol, Pyrazinamide, Vasicinone and Ethambutol)) from a medicinal plant Justicia adhatoda L for further consideration. Here, UBE2E3 is linked to lip and oral cavity carcinoma.