NFKB1 and neoplasm: Many tumor cells in the human body have been recognized as pro-oxidant and augment inflammatory reactions and oxidative stress.Elevated these oxidative stress upsurges the enduring capacity of the tumor cells by elevation and activation of mutations, signaling of redox reactions, and proinflammatory factors, chemokines, NF-kB, and cytokines [71-74].Antioxidants modify this intracellular redox status and thus elevating the effects of cytotoxic therapy.