However, IL6 KO inhibited tumor growth, lung metastasis, extended survival of animals bearing‐tumor xenografts (Figure S8E–H, Supporting Information), reduced MDSC recruitment, CD4+ and CD8+ T cell depletion (Figure S8I–K, Supporting Information), macrophage repression (Figure S8L, Supporting Information), and had no effect on the infiltration of B cells and NK cells (Figure S8M,N, Supporting Information). This evidence concerns the gene IL6 and neoplasm.