The most common non-hematological AEs were asthenia (13 of 18, 72.2%), fatigue (2 of 18,11.1%), anemia (6 of 18, 33.3%), decreased appetite (4 of 18, 22.2%), nausea (3 of 18, 16.7%), constipation (3 of 18, 16.7%), weight loss (3 of 18, 16.7%), increased blood cholesterol (8 of 18, 44.4%), increased blood triglycerides increase (6 of 18, 33.3%), increased aspartate aminotransferase (4 of 18, 22.2%), increased low-density lipoprotein (4 of 18, 22.2%), and increased alanine aminotransferase (3 of 18, 16.7%). The gene discussed is GPT; the disease is anemia (phenotype).