Only those mice receiving CAR-NKAE cells survived until the end of the experiment (127 days after treatment, 129 after MM cells infusion), and 25% (2/8) of them remained disease free with no bioluminescence signal (Fig. 7A and B) Flow cytometry for GFP-positive and CD138-positive cells in the bone marrow of these mice revealed no plasma cells (0.00%) or very small numbers (0.05%) of plasma cells (Fig. 7D). This evidence concerns the gene SDC1 and Miyoshi myopathy.