KLRK1 and hematologic disorder: Furthermore, NKG2DL are also expressed on immunosuppressive cells, such as regulatory T cells and myeloid-derived suppressor cells[34], making NKG2D-CAR treatment an attractive treatment option for both hematological malignancies and solid tumors [35, 36] both controlling the immunosuppressive environment and the development of the neovasculature [37].