Studies by Allgrove, Farrell [42] and Davison, Callister [47] found that prolonged cycling at 60% \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\dot{V}$$\end{document}V ̇O2max increased inflammatory markers (IL-6, IL-10 and IL-1ra and IL-6, blood leucocyte count and neutrophil count, respectively) but found no difference between CF supplementation or placebo. The gene discussed is IL6; the disease is cystic fibrosis.