MBL2 and hyperinsulinemic hypoglycemia, familial, 4: Patients with MBL concentrations ≥ 500 ng/mL and low IgG concentrations (MBL+/IgG− ) re-exacerbated most frequently (51%), followed by patients with MBL deficiency and low IgG (MBL-/IgG−, 37%) and MBL sufficient patients with normal IgG (MBL + /IgG + , 35%).