For the 49 patients who did not receive VTE prophylaxis, compared with non-AKI patients, AKI patients had longer prothrombin time (PT; P = 0.014), longer activated partial prothrombin time (APTT; P = 0.027), higher SIRS score (P = 0.001) and higher proportion of IMV (P = 0.030). This evidence concerns the gene F2 and acute kidney injury.