TGIF1 and breast cancer: To address the potential role of TGIF in human BC, also in the context of bone metastases, we analyzed TGIF protein expression by immunohistochemistry in 1197 human BC samples using a tissue microarray prepared from formalin-fixed paraffin-embedded (FFPE) tissue samples of BC patients treated with two different dose-dense schedules of adjuvant chemotherapy with or without the bisphosphonate ibandronate.