Out of an overall cohort of 613 HIES and 93 CMC patients analyzed by our laboratory, 322 had undergone Sanger sequencing for the target gene deemed most likely, revealing 91 STAT3, 39 DOCK8, and 5 PGM3 mutations in HIES and 23 STAT1 and 4 CARD9 mutations in the CMC cohort. The gene discussed is CARD9; the disease is chronic mucocutaneous candidiasis.