OXT and Cushing syndrome due to macronodular adrenal hyperplasia: The most significant results for the functional pathways associated with the DMRs in PWS included biological processes and pathways related to nervous system development, generation of neurons and neurogenesis, anatomical structure development, synapses, aldosterone synthesis, Cushing syndrome, cortisol synthesis, cholinergic synapse, oxytocin signaling and endocrine resistance (Table 3).