NMD inhibition has been reported in cancer, where it leads to the stabilization of transcripts that are important for tumorigenesis, such as KLF6 (Kruppel-like factor 6) in hepatocellular carcinoma and MALAT1 (metastasis-associated lung adenocarcinoma transcript 1) in gastric cancer [24, 25]. This evidence concerns the gene KLF6 and cancer.