We found that TFRC mRNA expression was elevated in 20 types of tumor, including breast invasive carcinoma (BRCA), colon adenocarcinoma (COAD), LIHC, and lung adenocarcinoma (LUAD) as compared to normal tissues, providing that upregulated TFRC is a common feature in cancers (Fig. 6A). Here, TFRC is linked to colon adenocarcinoma.