Subsequently, the expression level of OGFRP1 in normal human bronchial epithelial cell line 16-HBE and NSCLC cell lines (H1299, SPC-A-1, SK-MES-1, NCI-H520, 95D, A549) was tested, and the results showed that the expression level of OGFRP1 in all NSCLC cell lines was significantly higher than that in the 16-HBE cell line (Fig. 2A). This evidence concerns the gene OGFRP1 and non-small cell lung carcinoma.