GAD1 and Anxiety: With regard to anxiety, there were significant effects of time (F3.35-388.43 = 6.82; P < .001), group (F1.00-116.00 = 15.34; P < .001), and time-group interaction (F3.35-388.43 = 5.31; P = .001) on GAD-7 scores (Figure 3).