SOD2 and Behcet disease: A recent candidate gene study with 325 adults with BD and 392 healthy control (HC) adults identified that an interaction of 2 antioxidative enzyme single nucleotide polymorphisms (SNPs), superoxide dismutase 2 (SOD2) rs4880 and glutathione peroxidase 3 (GPX3) rs3792797, was associated with an increased risk for BD (Fullerton, 2010).