Direct correlation of 68Ga-PSMA-11-PET uptake with immunohistochemical PSMA expression in RPE specimen has been described only by Woythal et al. They demonstrated a significantly lower SUVmax in PCa RPE specimen (n = 31) which showed an immunoreactive score (IRS) smaller than 2 or a PSMA staining in less than 50% of the tumour cells [21]. This evidence concerns the gene FOLH1 and posterior cortical atrophy.