ENG and pulmonary arterial hypertension: Malhotra et al. investigated the concentrations of soluble endoglin, vascular endothelial growth factor receptor-1 (sVEGFR1), N-terminal brain natriuretic peptide and C-reactive protein in the peripheral blood of 97 PAH patients.51 Moreover, they obtained lung tissue from the aforementioned patients, which they also examined for endoglin expression and microvascular endothelium changes.