This motivated the development of drugs efficiently detaching BET proteins from chromatin as therapeutic molecules to treat cancer (Filippakopoulos et al., 2010; Dawson et al., 2011; Delmore et al., 2011; Mertz et al., 2011; Zuber et al., 2011), but at the same time they proved also to be effective in suppressing inflammation (Nicodeme et al., 2010). The gene discussed is DNER; the disease is cancer.