The cGAS-STING pathway activation has been shown to activate canonical and – in cancer cells – non-canonical nuclear factor kB (NF-kB), mitogen-activated protein (MAP) kinases, and signal transducer and activator of transcription (STAT) transcription factors (McWhirter et al., 2009; Bakhoum et al., 2018). Here, STING1 is linked to cancer.