Prognostic biomarkers in HCC have been identified: the overexpressions of XRCC5, IRF3, TRIM21, STAT6, DDX41, TBK1, XRCC6, TREX1, PRKDC, and STING are significantly related to the clinical stage and pathological grades of HCC (Qi et al., 2020). This evidence concerns the gene STING1 and hepatocellular carcinoma.