C-X-C motif chemokine receptor 4 (CXCR4) is a chemokine receptor that has been intensively studied because of its significant role in cellular functions, immune processes, growth and development, and liver disease (Qin L. et al., 2018; Zheng et al., 2018; Ullah, 2019; Yang et al., 2019). Here, CXCR4 is linked to liver disorder.