Some of the tested miRNAs have previously been shown to be targeted by GAS5 in osteosarcoma, such as miR-221 (Ye et al., 2017), miR-203a (Wang and Kong, 2018), miR-23a (Liu et al., 2020), and miR-663a (Yao et al., 2020; Zhao et al., 2020). This evidence concerns the gene GAS5 and osteosarcoma.