There are several reasons for this: Firstly, primary m6A antibody-based sequence approaches, a low-resolution mapping technology that cannot substantially distinguish m6Am from m6A, mistakenly assigned several m6Am-linked physiological effects to m6A. Many studies regarding FTO have demonstrated that m6A and m6Am are involved in the neuronal system, immune response, tumor genesis, and malignancy. This evidence concerns the gene FTO and neoplasm.